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Nerve Agent Precursor: Diisopropylamine

CA Index Name 2-Propanamine, N-(1-methylethyl)-
CAS Registry Number 108-18-9 RTECS Number IM4025000
EINECS Number
203-558-5 UN Transport Code 1158
ICSC Number
0449
CWC Schedule not listed

 

Warning Symbols
Flammable Harmful

 

Synonyms:
  • Bis(isopropyl)amine
  • N,N-Diisopropylamine
  • DIPA

CHEMICAL AND PHYSICAL PROPERTIES

Structural Formula

A clear liquid with a fishy odor
Molecular
Formula
C6H15N Molecular
Weight
101.2
Boiling
Point
84°C Melting
Point
-61°C
Vapor
Density
3.5 Liquid
Density
0.722
Vapor pressure
9.3 kPa at 20°C
Flammabe: flash point -7°C

 

NFPA Hazard Ratings
FIRE
3
HEALTH
3
REACTIVITY
0

SPECIAL
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Also refer to 2000 Emergency Response Guidebook (ERG2000) Guide 132.

 


Initial Isolation and Protective Action Distances

No specific recommendations

Health Hazards

Diisopropylamine, like all other lower alkyl amines istoxic and irritating. It can be irritating and toxic by ingestion and inhalation. Skin contact can cause burning and blistering and prolonged and repeated exposure can cause dermatitis. Inhalation can cause a burning sensation, cough. headache, laboured breathing, shortness of breath. and sore throat. Vision can be blurred. High levels of exposure can kill. Diisopropylamine is extremely flammable and decomposes on burning with the generation of toxic fumes including nitrogen oxides. It reacts violently with strong oxidants and mercury causing fire and explosion hazard. It also attacks copper, zinc alloys, aluminium, galvanized surfaces, and plastic. The solution in water is a strong base, it reacts violently with acid and is corrosive.

Risk and Safety Phrases.

INDUSTRIAL/COMMERCIAL USES

Diisopropylamine can be used as a base catalyst and in the curing of epoxy resins. It is also used in hide softening in leather processing. Its use in synthetic chemistry include herbicides such as Avadex and organophosphate and carbamate pesticides.

 

COMMENTS

Diisopropylamine is used in the synthesis of V-type nerve agents. The most important method for the manufacture of alkyl amines is the reaction of alkyl halides, such as propyl chloride, with ammonia. Alkyl amines can be manufactured by a number of other methods.

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